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Line a 9 x 13-inch baking pan with foil, set aside
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In a medium-sized heavy duty saucepan, combine sugars, butter, evaporated milk, pumpkin and pumpkin pie spice
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Stirring constantly, bring to a rolling boil over medium heat
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Continue to constantly stir and boil for 12-13 minutes, or until a candy thermometer reads 234-240 degrees f {soft boil stage}
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Immediately stir in white chocolate morsels, marshmallow crème, nuts and vanilla
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Stir quickly until morsels are melted and mixture is well combined, about 1 minute
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Poor mixture into prepared foil-lined pan
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Let sit until completely cooled, about 2 hours
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Lift from pan and cut into 1-inch pieces
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Store tightly covered in refrigerator